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Entrepreneurs of the Year: Jeffrey Hasday and Paul Shapiro

Fri Oct 20, 2023
The 2023 University of Maryland, Baltimore Entrepreneurs of the Year are: • Jeffrey Hasday, MD, the Dr. Herbert Berger Professor of Medicine and Division Head, Pulmonary and Critical Care Medicine at the University of Maryland School of Medicine and • Paul Shapiro, PhD, Professor, Department of Pharmaceutical Sciences and Associate Dean of Research and Advanced Graduate Studies in the University of Maryland School of Pharmacy.Hasday and Shapiro are co-inventors of technology that is focused on treatments for inflammatory diseases, including acute respiratory disease syndrome, or, ARDS, and has been licensed to GEn1E Lifesciences, a biotech company based in Silicon Valley.When they first met, Shapiro was working on developing novel drugs that target a class of enzymes called kinases — specifically ERK mitogen-activated protein kinases (MAPK) that are important in cancer — that instruct cells to perform certain functions and are implicated in many diseases.Hasday ,was working on the role of a related enzyme called p38 MAPK in acute respiratory distress syndrome (ARDS), a lung disease with high mortality and few available treatments.#ards #PharmacySchool #MedSchool